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The study found that the injection of ADSC-derived exosomes into the cavernous body of rats can promote the growth of endothelial cells and smooth muscle cells, inhibit cell apoptosis, alleviate tissue hypoxia, and promote the recovery of erectile function in rats (66, 67)
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The infected cells were subsequently resuspended in lysis buffer (containing 50 mM Tris, 10% sucrose, 50 µM ATP, 1 mM phenylmethylsulfonyl fluoride (PMSF), 5 mM dithiothreitol (DTT), 1% NP40, 10 mM imidazole, 1× protease inhibitor and phosphatase inhibitor, pH 7.0, with HCl)
Glutathione is an antioxidant tripeptide that plays a key role in supporting the bodyaTMs natural detoxification processes and defending cells against oxidative stress.